BioTi™: Biocompatible Flow Path
We’ve minimized the need for priming with a new titanium infused biocompatible hardware and frit that doesn’t interfere with protein or peptide integrity!
Overlaid Injections–Aggregate Analysis of mAb Sample
|Conditions for Both Columns:|
|Column:||bioZen 1.8 um SEC-3|
|Dimension:||150 x 4.6 mm|
|Mobile Phase:||50 mM Dipotassium phosphate + 100mM, Sodium Sulfate (pH 5.0)|
|Flow Rate:||0.3 mL/min|
|Injection Volume:||2 µL|
|Detection:||UV @ 280 nm|
|Sample:||1. γ-Globulin 5 mg/mL
2. Ovalbumin 1 mg/mL
We engineered our new titanium BioTi biocompatible hardware to give you back the hours, days, and weeks typically spent on column priming.– Jason Anspach, Ph.D.
Extend Column Lifetime with Biocompatible Guard Cartridge Systems
The new biocompatible SecurityGuard Standard and ULTRA cartridge systems remove unwanted contaminants before they clog your column or system. Each bioZen column has a matching guard to ensure workflow applicability.
With a single innovative product line spanning major biologics workflows, you can now gain some reprieve from juggling multiple catalogs, bookmarks, and vendors.With high quality particle chemistries designed and tested for biologics.
3 Particle Platforms
Thermally Modified Fully Porous
Uniform Particle Size Distribution
Using sol-gel processing techniques that incorporate nano structuring technology, a durable, homogeneous porous shell is grown on a solid silica core. This highly optimized process combined with industry leading column packing technology produces highly reproducible columns that generate extremely high efficiencies and sensitivity.
9 Particle Chemistries and Growing
Size Exclusion (SEC)
bioZen Intact C43.6 µm
Large pore core-shell particle for fast intact biologic entry. C4 stationary phase provides highly sought after low hydrophobic retention, especially important for highly retentive biologics.
bioZen Intact XB-C83.6 µm
Large pore core-shell particle for fast intact biologic entry. The XB-C8 Phase provides highly useful moderate hydrophobic selectivity.
bioZen SEC-31.8 µm
Extremely inert, high density fully porous particle with high efficiency and high molecular weight (HMW) separation range of 10 K – 700 kDa.
bioZen SEC-21.8 µm
Extremely inert, high density fully porous particle with high efficiency and low molecular weight (LMW) separation range of 1 K – 450 kDa.
bioZen PS-C181.6 µm and 3 µm
Excellent retention by combined positively charged surface ligand and C18 ligand.
bioZen XB-C181.7 µm and 2.6 µm
Overall retention of both acidic and basic peptides through C18 stationary phase.
bioZen Glycan2.6 µm
Provides optimal combination of high efficiency and selectivity for released glycans.